A busy schedule and
no time to get that tooth fixed?
Dr. Randall Cislo 885-8617
General Dentistry | M–Th 7am–7pm | Fri 7am-12pm
Parker Square, Waimea
HDS / DDP / AARP / HMSA / HMAA
7A
between Hualalai Road
and Kahaluu Beach Park
from 9 a.m. to 9 p.m.
Saturday.
On Hualalai Road :
— The section of road
between Alii Drive and
Kuakini Highway will
be closed from 6:30
a.m. Saturday to 12:30
a.m. Sunday. Access to
parking areas will be
restricted.
On Kuakini Highway:
— On Saturday, the
section between Palani
Road
and
Makala
Boulevard will be closed
from 6:30 a.m. to 5:30
p.m.; traffic won’t be
allowed on the stretch
between Palani and
Hualalai roads from6:30
a.m. to noon with south-
bound lanes in the area
closing at 10 a.m. and
remaining closed until
12:30 a.m. Sunday. The
section of road between
Palani Road heading
south toward Kahakai
Estates will only be open
to local traffic from 6:30
to 10:30 a.m. Saturday.
On Palani Road :
— The section of road
betweenKailua Pier and
King Kamehameha’s
Kona Beach Hotel
will be closed from
6 a.m. Thursday to 2
p.m. Sunday. The area
between the hotel and
Kuakini Highway will
be closed from 6 a.m.
Saturday to 12:30
a.m.
Sunday.
The
makai-bound lanes of
Palani Road between
Kuakini and Queen
Kaahumanu highways
will be closed from 6
a.m. Saturday until
12:30 a.m. Sunday.
Mauka-bound lanes on
Palani Road between
the two highways will
be closed from 6:30
a.m. Saturday to 12:30
a.m. Sunday.
On Makala
Boulevard:
— The stretch of road
between Kuakini and
Queen
Kaahumanu
highways is closed from
6:30 a.m. to 5:30 p.m.
Saturday.
Queen Kaahumanu
Highway will be
closed in the
following areas:
— Henry Street to
the Natural Energy
Laboratory of Hawaii
Authority will be closed
from 6:30 a.m. Saturday
to 12:30 a.m. Sunday.
— From NELHA to
Kawaihae Road, the
highway will be closed
from 7 a.m. to 5:30
p.m. Those traveling to
the airport on Saturday
should use Kaiminani
Drive and those travel-
ing to resorts should use
Waikoloa Road.
—
Akoni
Pule
Highway, between its
junction with Kawaihae
Road and Hawi, will be
closed between 8 a.m.
and 3:30 p.m. Access
to Hawi is via Kohala
Mountain Road from
Waimea.
For more informa-
tion, call the triathlon’s
road closure hotline at
334-3400.
IRONMAN:
Allow extra time to
arrive at your destination
CONTINUED FROM PAGE 1A
on his own recognizance
under the Hawaii Rules
of Penal Procedure,
McCabe said, making a
formal motion.
The rules say that,
unless the delay is the
result of the defendant
or the court finds “…
such compelling fact
or circumstance would
render such a release
to be against the inter-
est of justice,” a person
held that long has to be
released on their own
recognizance.
As a result Kaawa
will not have to post the
$25,000 bail set by the
court.
Matsunaga granted the
defense’s motion.
Kaawa’s preliminary
hearing is now set for
2:30 p.m. Oct. 12.
ROBBER:
Kaawa will not have to post the $25,000 bail
CONTINUED FROM PAGE 1A
For
more
information,
call the
triathlon’s
road closure
hotline at
334-3400.
“
“
3 Scientists Win Nobel Prize in Medicine
for Parasite-Fighting Therapies
Three scientists who used mod-
ern laboratory techniques to dis-
cover anti-parasitic drugs long
hidden in herbs and soil won
the Nobel Prize in Physiology or
Medicine on Monday.
Their drug therapies “have revo-
lutionized the treatment of some of
the most devastating parasitic dis-
eases,” the Nobel Committee of the
Karolinska Institute in Stockholm
said in announcing the winners.
They are William C. Campbell, for-
merly of New Jersey, and Satoshi
Omura of Japan, who share one-
half of the $960,000 award with
Tu Youyou of China.
Campbell and Omura devel-
oped Avermectin, the parent of
Ivermectin, a medicine that has
nearly eradicated river blindness
and radically reduced the inci-
dence of filariasis, which can cause
the disfiguring swelling of the
lymph system in the legs and lower
body known as elephantiasis.
Tu was inspired by Chinese tra-
ditional medicine in discovering
Artemisinin, a drug that is now
part of standard anti-malarial reg-
imens and that has reduced death
rates from the disease.
“These two discoveries have
provided humankind with pow-
erful new means to combat these
debilitating diseases that affect
hundreds of millions of people
annually,” the Nobel Committee
said in a statement. “The con-
sequences in terms of improved
human health and reduced
suffering are immeasurable”
because parasitic diseases “repre-
sent a huge barrier to improving
human health and well-being.”
Parasitic diseases are a threat
to an estimated one-third of the
world’s population, particular-
ly among the poor in sub-Saha-
ran Africa, South Asia and Latin
America. Insects transmit both
river blindness (black flies) and
malaria (mosquitoes).
Ivermectin and Artemisinin
are included in the World Health
Organization’s list of essential
medicines and are distributed
free or at low cost. The Nobel
Committee said it was not aware
of any active patents on the drugs.
In 1987 Merck, which had prof-
ited handsomely from use of
Ivermectin in domestic and farm
animals, began distributing the
drug free to people because those
who needed it the most could not
afford it.
Campbell and Omura collabo-
rated but worked independently
on different aspects of the discov-
ery of Avermectin.
Campbell was born in Ramelton,
Ireland, in 1930 and earned a Ph.D.
at the University of Wisconsin. He
worked for decades at the Merck
Institute for Therapeutic Research
before moving to Drew University
in Madison, New Jersey, as part of
a program where retired industrial
scientists direct research of indi-
vidual undergraduates. Five years
ago he moved to North Andover,
Massachusetts.
Campbell learned of his award
when a reporter awakened him.
“I thought he was kidding, and
when I asked how I could find out,
the reporter suggested the web-
site,” Campbell said in an interview.
Omura, who was born in 1935,
earned two Ph.D.s from the
University of Tokyo, in pharma-
ceutical sciences and chemistry. He
is emeritus professor at Kitasato
University in Tokyo. Omura
applied what the Nobel Committee
said were “extraordinary skills in
developing unique methods” for
scientifically characterizing natu-
ral products in Streptomyces bac-
teria found in soil. Bacterial cous-
ins have yielded antibiotics like
streptomycin.
At a news conference Monday
in Tokyo, Omura played down
his accomplishments, saying, “I
merely borrowed the power of
microbes.”
He said he was surprised by the
recognition.
“I never imagined I would win,”
he said. “If I had, I’d have worn a
nicer necktie.”
Omura carries a plastic bag
to collect soil samples. From
several thousand cultures of
Streptomyces he focused on the
50 he thought showed the most
promise against
BY LAWRENCE K. ALTMAN
THE ASSOCIATED PRESS
WEST HAWAII TODAY | TUESDAY, OCTOBER 6, 2015
These two
discoveries have
provided humankind
with powerful new
means to combat
these debilitating
diseases that affect
hundreds of millions
of people annually.
NOBEL COMMITTEE
“
“
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